R&D

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    No.55

    Anti-tumor Effects of anti-PD-1 Antibody, Pembrolizumab, in Humanized NSG PDX Mice Xenografted With Dedifferentiated Liposarcoma

    Sarcoma

    Anti-tumor Effects of anti-PD-1 Antibody, Pembrolizumab, in Humanized NSG PDX Mice Xenografted With Dedifferentiated Liposarcoma

    2020

    No.54

    Integrated whole liver histologic analysis of the allogeneic islet distribution and characteristics in a nonhuman primate model

    Islet

    Integrated whole liver histologic analysis of the allogeneic islet distribution and characteristics in a nonhuman primate model

    2020

    No.53

    Comparative study of human and cynomolgus T-cell depletion with rabbit anti-thymocyte globulin (rATG) treatment-for dose adjustment in a non-human primate kidney transplantation model

    Kidney Transplant

    Comparative study of human and cynomolgus T-cell depletion with rabbit anti-thymocyte globulin (rATG) treatment-for dose adjustment in a non-human primate kidney transplantation model

    2019

    No.52

    Multi-layer surface modification of pancreatic islets for magnetic resonance imaging using ferumoxytol.

    Islet

    Multi-layer surface modification of pancreatic islets for magnetic resonance imaging using ferumoxytol.

    2019

    No.51

    Relationships between Cytokine Levels and Disease Parameters during the Development of a Collagen-induced Arthritis Model in Cynomolgus Macaques (Macaca fascicularis).

    autoimmune disease

    Relationships between Cytokine Levels and Disease Parameters during the Development of a Collagen-induced Arthritis Model in Cynomolgus Macaques (Macaca fascicularis).

    2019

    No.50

    Combination therapy with c-met inhibitor and TRAIL enhances apoptosis in dedifferentiated liposarcoma patient-derived cells

    Sarcoma

    Combination therapy with c-met inhibitor and TRAIL enhances apoptosis in dedifferentiated liposarcoma patient-derived cells

    2019

    No.49

    Reconstituting human cutaneous regeneration in humanized mice under endothelial cell therapy

    Hu-mouse

    Reconstituting human cutaneous regeneration in humanized mice under endothelial cell therapy

    2019

    No.48

    Reduced variability in pharmacokinetics of tacrolimus following intramuscular injection compared to oral administration in Cynomolgus monkeys: investigating optimal dosing regimens

    Non-Human Primates

    Reduced variability in pharmacokinetics of tacrolimus following intramuscular injection compared to oral administration in Cynomolgus monkeys: investigating optimal dosing regimens

    2019

    No.47

    Establishment of a novel PDX mouse model and evaluation of the tumor suppression efficacy of bortezomib against liposarcoma

    Sarcoma

    Establishment of a novel PDX mouse model and evaluation of the tumor suppression efficacy of bortezomib against liposarcoma

    2019

    No.46

    Small molecule-mediated reprogramming of human hepatocytes into bipotent progenitor cells

    Hepatocyte

    Small molecule-mediated reprogramming of human hepatocytes into bipotent progenitor cells

    2019

    No.45

    CKD-506, a novel HDAC6-selective inhibitor, improves renal outcomes and survival in a mouse model of systemic lupus erythematosus.

    autoimmune disease

    CKD-506, a novel HDAC6-selective inhibitor, improves renal outcomes and survival in a mouse model of systemic lupus erythematosus.

    2018

    No.44

    Ectopic vascularized bone formation by human umbilical cord-derived mesenchymal stromal cells expressing bone morphogenetic factor-2 and endothelial cells

    MSC

    Ectopic vascularized bone formation by human umbilical cord-derived mesenchymal stromal cells expressing bone morphogenetic factor-2 and endothelial cells

    2018

    No.43

    Effects of Transplanted Islets Nano-Encapsulated with Hyperbranched Polyethylene Glycol and Heparin on Microenvironment Reconstruction and Glucose Control.

    Islet

    Effects of Transplanted Islets Nano-Encapsulated with Hyperbranched Polyethylene Glycol and Heparin on Microenvironment Reconstruction and Glucose Control.

    2018

    No.42

    Polymeric nano-shielded islets with heparin-polyethylene glycol in a non-human primate model

    Islet

    Polymeric nano-shielded islets with heparin-polyethylene glycol in a non-human primate model

    2018

    No.41

    Three-Dimensional Bioprinting of Hepatic Structures with Directly Converted Hepatocyte-Like Cells.

    Hepatocyte

    Three-Dimensional Bioprinting of Hepatic Structures with Directly Converted Hepatocyte-Like Cells.

    2018

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